Anti-Phospho-PDPK1 (Ser241) Rabbit Polyclonal Antibody
Product Information
Downloads & Supports
Target
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PDPK1
Host
Storage
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Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
Clone Number
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-
Isotype
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IgG
Reactivity
Application
Application Details
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WB: 1/500-1/1000 IHC: 1/50-1/100 ICC: 1/100-1/200
Immunogen
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Synthetic peptide of human PDPK1
Molecular Weight
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Calculated MW: 63 kDa; Observed MW: 63 kDa
Formulation
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Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.
Form
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Liquid
Gene ID
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5170
Uniprot ID
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O15530
Background
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Phosphoinositide-dependent protein kinase 1 (PDK1) plays a central role in many signal transduction pathways including the activation of Akt and the PKC isoenzymes p70 S6 kinase and RSK. Through its effects on these kinases, PDK1 is involved in the regulation of a wide variety of processes, including cell proliferation, differentiation and apoptosis.
Research Area
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Signal Transduction
Synonyms
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PDPK1; PDK1; 3-phosphoinositide-dependent protein kinase 1; hPDK1