Anti-Phospho-PBK/TOPK (Thr9) Rabbit Monoclonal Antibody
Product Information
Downloads & Supports
Target
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PBK
Host
Storage
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Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
Clone Number
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R21-1A-8
Isotype
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IgG
Reactivity
Application
Application Details
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WB: 1/500-1/1000 IHC: 1/100-1/200
Immunogen
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A synthesized peptide derived from human Phospho-PBK/TOPK (Thr9)
Molecular Weight
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Calculated MW:36kDa;Observed MW:40kDa
Formulation
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Liquid in PBS , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form
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Liquid
Gene ID
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55872
Uniprot ID
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Q96KB5
Background
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Phosphorylates MAP kinase p38. Seems to be active only in mitosis. May also play a role in the activation of lymphoid cells. When phosphorylated, forms a complex with TP53, leading to TP53 destabilization and attenuation of G2/M checkpoint during doxorubicin-induced DNA damage.
Research Area
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Cell Biology
Synonyms
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CT84; MAPKK like protein kinase; Nori3; PBK; PDZ binding kinas; Serine/threonine protein kinase; SPK; TOPK;