Anti-Phospho-p95 (Ser343) Rabbit Monoclonal Antibody
Product Information
Downloads & Supports
Target
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NBN
Host
Storage
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Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
Clone Number
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R04-5S5
Isotype
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IgG
Reactivity
Application
Application Details
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WB: 1/500-1/1000 IF: 1/50-1/200 IP: 1/50
Immunogen
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A synthesized peptide derived from human Phospho-p95/NBS1 (S343)
Molecular Weight
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Calculated MW: 85 kDa
Formulation
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Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form
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Liquid
Gene ID
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4683
Uniprot ID
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O60934
Background
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NBS1 is a member of the MRE11/RAD50 double-strand break repair complex. Involved in DNA double-strand break repair and DNA damage-induced checkpoint activation. Mutation results in the Nijmegen breakage syndrome (NBS), an autosomal recessive chromosomal instability syndrome.
Research Area
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Epigenetics and Nuclear Signaling
Synonyms
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NBN; NBS; NBS1; P95; Nibrin; Cell cycle regulatory protein p95; Nijmegen breakage syndrome protein 1