Anti-Phospho-Nrf2 (Ser40) Rabbit Monoclonal Antibody
Product Information
Downloads & Supports
Target
-
NFE2L2
Host
Storage
-
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
Clone Number
-
R03-4A1
Isotype
-
IgG
Reactivity
Application
Application Details
-
WB-1:1000-1:5000; IHC-P-1:100-1:500; ICC/IF-1:100-1:200; FC-1:50-1:100
Immunogen
-
A synthesized peptide derived from human Phospho-Nrf2 (S40)
Molecular Weight
-
Calculated MW: 68 kDa; Observed MW: 90 kDa
Formulation
-
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form
-
Liquid
Gene ID
-
4780
Uniprot ID
-
Q16236
Background
-
Transcription activator that binds to antioxidant response (ARE) elements in the promoter regions of target genes. Important for the coordinated up-regulation of genes in response to oxidative stress. May be involved in the transcriptional activation of genes of the beta-globin cluster by mediating enhancer activity of hypersensitive site 2 of the beta-globin locus control region.
Research Area
-
Epigenetics and Nuclear Signaling
Synonyms
-
NFE2L2; NRF2; Nuclear factor erythroid 2-related factor 2; NF-E2-related factor 2; NFE2-related factor 2; HEBP1; Nuclear factor; erythroid derived 2; like 2