Anti-Phospho-Myosin Phosphatase (Thr853) Rabbit Polyclonal Antibody
Product Information
Downloads & Supports
Target
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PPP1R12A
Host
Storage
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Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
Clone Number
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-
Isotype
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IgG
Reactivity
Application
Application Details
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WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200 ELISA: 1/10000
Immunogen
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The antiserum was produced against synthesized peptide derived from human MYPT1 around the phosphorylation site of Thr853.
Molecular Weight
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Calculated MW: 115 kDa; Observed MW: 130 kDa
Formulation
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Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.
Form
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Liquid
Gene ID
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4659
Uniprot ID
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O14974
Background
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Key regulator of protein phosphatase 1C (PPP1C). Mediates binding to myosin. As part of the PPP1C complex, involved in dephosphorylation of PLK1. Capable of inhibiting HIF1AN-dependent suppression of HIF1A activity.
Research Area
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Signal Transduction
Synonyms
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PPP1R12A; MBS; MYPT1; Protein phosphatase 1 regulatory subunit 12A; Myosin phosphatase-targeting subunit 1; Myosin phosphatase target subunit 1; Protein phosphatase myosin-binding subunit