Anti-Phospho-mTOR (Ser2448) Rabbit Monoclonal Antibody
Product Information
Downloads & Supports
Target
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MTOR
Host
Storage
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Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
Clone Number
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R13-9D-7
Isotype
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IgG
Reactivity
Application
Application Details
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WB: 1/500-1/1000 IHC: 1/100-1/200
Immunogen
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A synthesized peptide derived from human Phospho-mTOR (S2448)
Molecular Weight
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Calculated MW: 289 kDa;Observed MW:289kDa
Formulation
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Liquid in PBS , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form
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Liquid
Gene ID
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2475
Uniprot ID
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P42345
Background
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An atypical kinase belonging to the PIKK family of kinases. Controls cell growth through protein synthesis regulation. Downstream of PI3K/Akt pathway and required for cell survival. Acts as the target for the cell-cycle arrest and immunosuppressive effects of the FKBP12-rapamycin complex.
Research Area
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Cell Biology
Synonyms
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FRAP; FRAP1; FRAP2; RAFT1; Rapamycin target protein; kinase mTOR;