Anti-Phospho-mTOR (Ser2448) Rabbit Monoclonal Antibody

Anti-Phospho-mTOR (Ser2448) Rabbit Monoclonal Antibody
Anti-Phospho-mTOR (Ser2448) Rabbit Monoclonal Antibody
Anti-Phospho-mTOR (Ser2448) Rabbit Monoclonal Antibody
Anti-Phospho-mTOR (Ser2448) Rabbit Monoclonal Antibody
Anti-Phospho-mTOR (Ser2448) Rabbit Monoclonal Antibody
Anti-Phospho-mTOR (Ser2448) Rabbit Monoclonal Antibody

Anti-Phospho-mTOR (Ser2448) Rabbit Monoclonal Antibody

Rabbit IgG Monoclonal for MTOR detection, Test with WB, IHC-P in Human, Mouse

Reactivity
  • Human
  • Mouse
Application
  • WB
  • IHC-P
Host
  • Rabbit
Catalog Number
    ABXB61241
$370.00

Shipping To:
United States

Product Information

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Target
    MTOR
Host
  • Rabbit
Storage
    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
  • Monoclonal
Clone Number
    R08-7G7
Isotype
    IgG
Reactivity
  • Human
  • Mouse
Application
  • WB
  • IHC-P
Application Details
    WB: 1/500-1/1000 IHC: 1/50-1/100
Immunogen
    A synthetic phosphopeptide corresponding to residues surrounding Ser2448 of human mTOR
Molecular Weight
    Calculated MW: 289 kDa; Observed MW: 289 kDa
Formulation
    50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
Form
    Liquid
Gene ID
    2475
Uniprot ID
    P42345
Background
    An atypical kinase belonging to the PIKK family of kinases. Controls cell growth through protein synthesis regulation. Downstream of PI3K/Akt pathway and required for cell survival. Acts as the target for the cell-cycle arrest and immunosuppressive effects of the FKBP12-rapamycin complex.
Research Area
    Cell Biology
Synonyms
    MTOR; FRAP; FRAP1; FRAP2; RAFT1; RAPT1; Serine/threonine-protein kinase mTOR; FK506-binding protein 12-rapamycin complex-associated protein 1; FKBP12-rapamycin complex-associated protein; Mammalian target of rapamycin; mTOR; Mechanistic tar
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Western blot analysis of Phospho-mTOR (Ser2448) in Hela, Hela+EGF lysates using Phospho-mTOR (Ser2448) antibody.
Western blot analysis of mTOR (Phospho-Ser2448) in 3t3 lysates using mTOR (Phospho-Ser2448) antibody.
Immunohistochemistry analysis of paraffin-embedded Human lung cancer using Phospho-mTOR (Ser2448) antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.