Anti-Phospho-MDM2 (Ser166) Rabbit Monoclonal Antibody
Product Information
Downloads & Supports
Target
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MDM2
Host
Storage
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Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
Clone Number
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R08-8C7
Isotype
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IgG
Reactivity
Application
Application Details
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WB: 1/500-1/1000 IHC: 1/50-1/100
Immunogen
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A synthetic phosphopeptide corresponding to residues surrounding Ser166 of human MDM2
Molecular Weight
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Calculated MW: 55 kDa; Observed MW: 90 kDa
Formulation
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50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
Form
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Liquid
Gene ID
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4193
Uniprot ID
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Q00987
Background
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E3 ubiquitin-protein ligase that mediates ubiquitination of p53/TP53, leading to its degradation by the proteasome.
Research Area
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Neuroscience
Synonyms
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Double minute 2 protein; Hdm2; Oncoprotein Mdm2