Anti-Phospho-IRS1 (Ser639) Rabbit Polyclonal Antibody

Anti-Phospho-IRS1 (Ser639) Rabbit Polyclonal Antibody
Anti-Phospho-IRS1 (Ser639) Rabbit Polyclonal Antibody
Anti-Phospho-IRS1 (Ser639) Rabbit Polyclonal Antibody
Anti-Phospho-IRS1 (Ser639) Rabbit Polyclonal Antibody

Anti-Phospho-IRS1 (Ser639) Rabbit Polyclonal Antibody

Rabbit IgG Polyclonal for IRS1 detection, Test with WB, IHC-P, ELISA in Human, Mouse, Rat

Reactivity
  • Human
  • Mouse
  • Rat
Application
  • WB
  • IHC-P
  • ELISA
Host
  • Rabbit
Catalog Number
    ABXB05474
$370.00

Shipping To:
United States

Product Information

Downloads & Supports

Target
    IRS1
Host
  • Rabbit
Storage
    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
  • Polyclonal
Clone Number
    -
Isotype
    IgG
Reactivity
  • Human
  • Mouse
  • Rat
Application
  • WB
  • IHC-P
  • ELISA
Application Details
    WB: 1/500-1/1000 IHC: 1/50-1/100 ELISA: 1/10000
Immunogen
    The antiserum was produced against synthesized peptide derived from human IRS-1 around the phosphorylation site of Ser639.
Molecular Weight
    Calculated MW: 132 kDa; Observed MW: 150 kDa
Formulation
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.
Form
    Liquid
Gene ID
    3667
Uniprot ID
    P35568
Background
    May mediate the control of various cellular processes by insulin. When phosphorylated by the insulin receptor binds specifically to various cellular proteins containing SH2 domains such as phosphatidylinositol 3-kinase p85 subunit or GRB2. Activates phosphatidylinositol 3-kinase when bound to the regulatory p85 subunit .
Research Area
    Tags & Cell Markers
Synonyms
    IRS1; Insulin receptor substrate 1; IRS-1
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Product Image

Western blot analysis of Phospho-IRS1 (Ser639) in various lysates using Phospho-IRS1 (Ser639).
Immunohistochemistry analysis of paraffin-embedded Human breast carcinoma, using IRS1 (Phospho-Ser639).High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval. Sample with blocking peptide on the right.