Anti-Phospho-IRF3 (Ser386) Rabbit Polyclonal Antibody
Product Information
Downloads & Supports
Target
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IRF3
Host
Storage
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Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
Clone Number
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-
Isotype
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IgG
Reactivity
Application
Application Details
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WB: 1/500-1/1000
Immunogen
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Synthetic peptide of human IRF3
Molecular Weight
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Calculated MW: 47 kDa; Observed MW: 55 kDa
Formulation
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Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.
Form
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Liquid
Gene ID
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3661
Uniprot ID
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Q14653
Background
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IRFs comprise a family of transcription factors that function within the Jak/Stat pathway to regulate interferon (IFN) and IFN-inducible gene expression in response to viral infection. IRF-3 can inhibit cell growth and plays a critical role in controlling the expression of genes in the innate immune response.
Research Area
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Signal Transduction
Synonyms
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IRF3; Interferon regulatory factor 3; IRF-3