Anti-Phospho-Histone H3 (Thr3) Rabbit Polyclonal Antibody
Product Information
Downloads & Supports
Target
-
H3-3A
Host
Storage
-
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
Clone Number
-
-
Isotype
-
IgG
Reactivity
Application
Application Details
-
WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200 FC: 1/50-1/100
Immunogen
-
A synthesized peptide derived from human Phospho-Histone H3 (T3)
Molecular Weight
-
Calculated MW: 15 kDa; Observed MW: 15 kDa
Formulation
-
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form
-
Liquid
Gene ID
-
3020
Uniprot ID
-
P84243
Background
-
H3 Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
Research Area
-
Epigenetics and Nuclear Signaling
Synonyms
-
H3F3; H3.3A