Anti-Phospho-GSK3 (Tyr279/Tyr216) Rabbit Polyclonal Antibody
Product Information
Downloads & Supports
Target
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GSK3A
Host
Storage
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Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
Clone Number
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-
Isotype
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IgG
Reactivity
Application
Application Details
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WB: 1/500-1/1000 IHC: 1/50-1/100 ICC: 1/100-1/200
Immunogen
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Synthetic peptide of human GSK3A
Molecular Weight
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Calculated MW: 51 kDa; Observed MW: 46,51 kDa
Formulation
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Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.
Form
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Liquid
Gene ID
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2931
Uniprot ID
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P49840
Background
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GSK3A a proline-directed protein kinase of the GSK family. Implicated in the control of several regulatory proteins including glycogen synthase, Myb, and c-Jun. GSK3 and GSK3 have similar functions. GSK3 phophorylates tau, the principal component of neurofibrillary tangles in Alzheimer disease and is required for maximal production of amyloid plaque peptides by secretase.
Research Area
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Neuroscience
Synonyms
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Serine/threonine-protein kinase GSK3A