Anti-Phospho-GSK3 (alpha + beta)(Tyr216/Tyr279) Rabbit Monoclonal Antibody
Product Information
Downloads & Supports
Target
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GSK3A
Host
Storage
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Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
Clone Number
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R47-6P-9
Isotype
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IgG
Reactivity
Application
Application Details
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WB: 1/500-1/1000 IHC: 1/100-1/200 IF: 1/50-1/200 IP: 1/50
Immunogen
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A synthesized peptide derived from human Phospho-GSK3 (alpha + beta)(Y216 + Y279)
Molecular Weight
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Calculated MW:51kDa;Observed MW:51kDa
Formulation
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Liquid in PBS , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form
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Liquid
Gene ID
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2931
Uniprot ID
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P49840
Background
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GSK3A a proline-directed protein kinase of the GSK family. Implicated in the control of several regulatory proteins including glycogen synthase, Myb, and c-Jun. GSK3 and GSK3 have similar functions. GSK3 phophorylates tau, the principal component of neurofibrillary tangles in Alzheimer disease and is required for maximal production of amyloid plaque peptides by secretase.
Research Area
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Cell Biology
Synonyms
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Glycogen synthase kinase-3 alpha; GSK-3 alpha; GSK3A