Anti-Phospho-Glycogen synthase (Ser641) Rabbit Monoclonal Antibody
Product Information
Downloads & Supports
Target
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GYS1
Host
Storage
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Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
Clone Number
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R03-3A1
Isotype
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IgG
Reactivity
Application
Application Details
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WB: 1/500-1/1000 IHC: 1/50-1/100 IP: 1/20
Immunogen
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A synthetic phosphopeptide corresponding to residues surrounding Ser641 of human Glycogen synthase 1/GYS1
Molecular Weight
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Calculated MW: 84 kDa; Observed MW: 84 kDa
Formulation
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50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
Form
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Liquid
Gene ID
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2997
Uniprot ID
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P13807
Background
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Transfers the glycosyl residue from UDP-Glc to the non-reducing end of alpha-1,4-glucan. Allosteric activation by glucose-6-phosphate. Phosphorylation reduces the activity towards UDP-glucose. When in the non-phosphorylated state, glycogen synthase does not require glucose-6-phosphate as an allosteric activator; when phosphorylated it does.
Research Area
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Signal Transduction
Synonyms
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GYS1; GYS; Glycogen [starch] synthase; muscle