Anti-Phospho-Estrogen Receptor alpha (Ser118) Rabbit Monoclonal Antibody

Anti-Phospho-Estrogen Receptor alpha (Ser118) Rabbit Monoclonal Antibody
Anti-Phospho-Estrogen Receptor alpha (Ser118) Rabbit Monoclonal Antibody
Anti-Phospho-Estrogen Receptor alpha (Ser118) Rabbit Monoclonal Antibody
Anti-Phospho-Estrogen Receptor alpha (Ser118) Rabbit Monoclonal Antibody
Anti-Phospho-Estrogen Receptor alpha (Ser118) Rabbit Monoclonal Antibody
Anti-Phospho-Estrogen Receptor alpha (Ser118) Rabbit Monoclonal Antibody

Anti-Phospho-Estrogen Receptor alpha (Ser118) Rabbit Monoclonal Antibody

Rabbit IgG Monoclonal for ESR1 detection, Test with WB, IHC-P, ICC/IF in Human

Reactivity
  • Human
Application
  • WB
  • IHC-P
  • ICC
  • IF
Host
  • Rabbit
Catalog Number
    ABXB62754
$370.00

Shipping To:
United States

Product Information

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Target
    ESR1
Host
  • Rabbit
Storage
    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
  • Monoclonal
Clone Number
    R03-3T5
Isotype
    IgG
Reactivity
  • Human
Application
  • WB
  • IHC-P
  • ICC
  • IF
Application Details
    WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200
Immunogen
    A synthesized peptide derived from human ER alpha
Molecular Weight
    Calculated MW: 66 kDa; Observed MW: 66 kDa
Formulation
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form
    Liquid
Gene ID
    2099
Uniprot ID
    P03372
Background
    ER (estrogen receptor 1) a member of the steroid receptor superfamily, contains highly conserved DNA binding (DBD) and ligand binding domains (LBD). Through its estrogen-independent and estrogen-dependent activation domains (AF-1 and AF-2, respectively), ER regulates transcription by recruiting coactivator proteins and interacting with general transcriptional machinery. Phosphorylation provides an important mechanism to regulate ER activity. ER is phosphorylated on multiple sites.
Research Area
    Signal Transduction
Synonyms
    ESR1; Era; Eralpha; Estrogen receptor; Estradiol receptor; ER-alpha; Estrogen receptor 1; NR3A1; ER; ESR; ESRA; Estrogen receptor alpha
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Product Image

Western blot analysis of Phospho-ER alpha (S118) in (1) MCF-7 lysates; (2) MCF-7 lysates treated with bEstradiol and EGF using Phospho-Estrogen Receptor alpha (Ser118) antibody.
Immunohistochemistry analysis of paraffin-embedded Human kidney using Phospho-ER alpha (S118) antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.
Immunofluorescence analysis of Phospho-Estrogen Receptor alpha (Ser118) in MCF-7 treated with EGF using Phospho-ER alpha (S118) antibody.