Anti-Phospho-EGFR (Tyr1068) Rabbit Monoclonal Antibody
Product Information
Downloads & Supports
Target
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EGFR
Host
Storage
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Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
Clone Number
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R39-2V-1
Isotype
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IgG
Reactivity
Application
Application Details
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WB: 1/500-1/1000 IHC: 1/100-1/200 IF: 1/50-1/200
Immunogen
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A synthesized peptide derived from human Phospho-EGFR (Y1068)
Molecular Weight
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Calculated MW: 134 kDa;Observed MW:170kDa
Formulation
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Liquid in PBS , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form
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Liquid
Gene ID
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1956
Uniprot ID
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P00533
Background
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Receptor for epidermal growth factor (EGF) and related growth factors including TGF-alpha, amphiregulin, betacellulin, heparin-binding EGF-like growth factor, GP30 and vaccinia virus growth factor. Is involved in the control of cell growth and differentiation. . A single-pass transmembrane tyrosine kinase. Ligand binding to this receptor results in receptor dimerization, autophosphorylation (in trans), activation of various downstream signaling molecules and lysosomal degradation. Can be phosphorylated and activated by Src.
Research Area
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Signal Transduction
Synonyms
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ERBB1, Epidermal growth factor receptor precursor;Receptor protein-tyrosine kinase ErbB-1; kinase EGFR; HER1; EGFR; SA7; NISBD2;