Anti-Phospho-delta 1 Catenin (Thr916) Rabbit Monoclonal Antibody
Product Information
Downloads & Supports
Target
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CTNND1
Host
Storage
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Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
Clone Number
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R07-5A6
Isotype
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IgG
Reactivity
Application
Application Details
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WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200
Immunogen
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A synthetic phosphopeptide corresponding to residues surrounding Thr916 of human delta 1 Catenin/CAS
Molecular Weight
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Calculated MW: 108 kDa; Observed MW: 100 kDa
Formulation
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50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
Form
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Liquid
Gene ID
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1500
Uniprot ID
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O60716
Background
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Catenin δ-1 (p120 catenin) has an amino-terminal coiled-coil domain followed by a regulatory domain containing multiple phosphorylation sites and a central Armadillo repeat domain of ten linked 42-amino acid repeats. The carboxy-terminal tail has no known function. Catenin δ-1 fulfills critical roles in the regulation of cell-cell adhesion as it regulates E-cadherin turnover at the cell surface to determine the level of E-cadherin available for cell-cell adhesion.
Research Area
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Cell Biology
Synonyms
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CAS; p120; BCDS2; CTNND; P120CAS; P120CTN; p120(CAS); p120(CTN)