Anti-Phospho-Chk1 (Serer280) Rabbit Monoclonal Antibody
Product Information
Downloads & Supports
Target
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CHEK1
Host
Storage
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Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
Clone Number
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R32-4D-1
Isotype
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IgG
Reactivity
Application
Application Details
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WB: 1/500-1/1000
Immunogen
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A synthesized peptide derived from human Phospho-Chk1 (S280)
Molecular Weight
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Calculated MW: 54 kDa;Observed MW:54kDa
Formulation
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Liquid in PBS , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form
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Liquid
Gene ID
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1111
Uniprot ID
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O14757
Background
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Serine/threonine-protein kinase which is required for checkpoint-mediated cell cycle arrest and activation of DNA repair in response to the presence of DNA damage or unreplicated DNA. May also negatively regulate cell cycle progression during unperturbed cell cycles.
Research Area
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Epigenetics and Nuclear Signaling
Synonyms
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Checkpoint kinase 1; Chek1; Chk1; rad27;