Anti-Phospho-CDK1/2 (Thr14) Rabbit Monoclonal Antibody
Product Information
Downloads & Supports
Target
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CDK1/CDK2/
Host
Storage
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Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
Clone Number
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R06-1A5
Isotype
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IgG
Reactivity
Application
Application Details
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WB: 1/500-1/1000 IHC: 1/50-1/100 IP: 1/20
Immunogen
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A synthetic phosphopeptide corresponding to residues surrounding Thr14 of human Cdk1/2
Molecular Weight
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Calculated MW: 34 kDa; Observed MW: 34 kDa
Formulation
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50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
Form
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Liquid
Gene ID
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983/1017
Uniprot ID
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P06493/P24941
Background
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Cdk2 is a member of the Ser/Thr protein kinase family. It is highly similar to the gene products of S. cerevisiae cdc28, and S. pombe cdc2. Cdk2 is closely related to cdc2 (cdk1) which has proved useful as a marker of proliferation. Cdk1 and Cdk2 are a catalytic subunits of the highly conserved protein kinase complex known as M-phase promoting factor (MPF), which is essential for G1/S and G2/M phase transitions of eukaryotic cell cycle.
Research Area
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Cell Biology
Synonyms
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CDKN2; p33(CDK2)