Anti-Phospho-Caveolin 1 (Tyr14) Rabbit Polyclonal Antibody
Product Information
Downloads & Supports
Target
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CAV1
Host
Storage
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Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
Clone Number
-
-
Isotype
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IgG
Reactivity
Application
Application Details
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WB: 1/500-1/1000 ICC: 1/100-1/200
Immunogen
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Synthetic peptide of human CAV1
Molecular Weight
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Calculated MW: 20 kDa; Observed MW: 24 kDa
Formulation
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Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.
Form
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Liquid
Gene ID
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857
Uniprot ID
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Q03135
Background
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Caveolin-1 may act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity (By similarity). Involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation. Its binding to DPP4 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependent manner. Recruits CTNNB1 to caveolar membranes and may regulate CTNNB1-mediated signaling through the Wnt pathway.
Research Area
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Cardiovascular
Synonyms
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CAV1; CAV; Caveolin-1