Anti-Phospho-c-Met (Tyr1349) Rabbit Monoclonal Antibody
Product Information
Downloads & Supports
Target
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MET
Host
Storage
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Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
Clone Number
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R05-3D6
Isotype
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IgG
Reactivity
Application
Application Details
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WB: 1/500-1/1000 IP: 1/20
Immunogen
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A synthetic phosphopeptide corresponding to residues surrounding Tyr1349 of human Met
Molecular Weight
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Calculated MW: 156 kDa; Observed MW: 170,140 kDa
Formulation
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50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
Form
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Liquid
Gene ID
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4233
Uniprot ID
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P08581
Background
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The proto-oncogene MET product is the hepatocyte growth factor receptor and encodes tyrosine-kinase activity. The primary single chain precursor protein is post-translationally cleaved to produce the alpha and beta subunits, which are disulfide linked to form the mature receptor.
Research Area
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Signal Transduction
Synonyms
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MET; Hepatocyte growth factor receptor; HGF receptor; HGF/SF receptor; Proto-oncogene c-Met; Scatter factor receptor; SF receptor; Tyrosine-protein kinase Met