Anti-Phospho-c-Jun (Ser73)+JunD (Ser100) Rabbit Monoclonal Antibody
Product Information
Downloads & Supports
Target
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JUN/JUND
Host
Storage
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Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
Clone Number
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R27-9A-9
Isotype
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IgG
Reactivity
Application
Application Details
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WB: 1/500-1/1000 IHC: 1/100-1/200 IP: 1/50
Immunogen
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A synthesized peptide derived from human Phospho-c-Jun (S73)+JunD (S100)
Molecular Weight
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Calculated MW: 36 kDa;Observed MW:38,42,45kDa
Formulation
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Liquid in PBS , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form
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Liquid
Gene ID
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3725/3727
Uniprot ID
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P05412,P17535
Background
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Transcription factor that recognizes and binds to the enhancer heptamer motif 5'-TGA[CG]TCA-3' (PubMed:10995748, PubMed:22083952). Promotes activity of NR5A1 when phosphorylated by HIPK3 leading to increased steroidogenic gene expression upon cAMP signaling pathway stimulation (PubMed:17210646). Involved in activated KRAS-mediated transcriptional activation of USP28 in colorectal cancer (CRC) cells (PubMed:24623306). Binds to the USP28 promoter in colorectal cancer (CRC) cells (PubMed:24623306).
Research Area
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Epigenetics and Nuclear Signaling
Synonyms
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JunD; c-Jun;