Anti-Phospho-c-Jun (Ser63) Rabbit Monoclonal Antibody
Product Information
Downloads & Supports
Target
-
JUN
Host
Storage
-
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
Clone Number
-
R07-3G7
Isotype
-
IgG
Reactivity
Application
Application Details
-
WB: 1/500-1/1000 IHC: 1/50-1/100
Immunogen
-
A synthetic phosphopeptide corresponding to residues surrounding Ser63 of human c-Jun
Molecular Weight
-
Calculated MW: 36 kDa; Observed MW: 43 kDa
Formulation
-
50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
Form
-
Liquid
Gene ID
-
3725
Uniprot ID
-
P05412
Background
-
c-jun is a transcription factor that recognizes and binds to the enhancer heptamer motif 5'-TGA[CG]TCA-3'. Promotes activity of NR5A1 when phosphorylated by HIPK3 leading to increased steroidogenic gene expression upon cAMP signaling pathway stimulation.
Research Area
-
Epigenetics and Nuclear Signaling
Synonyms
-
Transcription factor AP-1; Activator protein 1; AP1; Proto-oncogene c-Jun; V-jun avian sarcoma virus 17 oncogene homolog; p39