Anti-Phospho-Bad (Ser136) Rabbit Polyclonal Antibody
Product Information
Downloads & Supports
Target
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Bad
Host
Storage
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Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
Clone Number
-
-
Isotype
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IgG
Reactivity
Application
Application Details
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WB: 1/500-1/1000 IHC: 1/50-1/100
Immunogen
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Peptide sequence around phosphorylation site of serine136 (S-R-S(p)-A-P) derived from Mouse BAD.
Molecular Weight
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Calculated MW: 22 kDa; Observed MW: 22 kDa
Formulation
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Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.
Form
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Liquid
Gene ID
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12015
Uniprot ID
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Q61337
Background
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Promotes cell death. Successfully competes for the binding to Bcl-X(L), Bcl-2 and Bcl-W, thereby affecting the level of heterodimerization of these proteins with BAX. Can reverse the death repressor activity of Bcl-X(L), but not that of Bcl-2. Appears to act as a link between growth factor receptor signaling and the apoptotic pathways.
Research Area
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Cell Biology
Synonyms
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Bbc2