Anti-PF4 Rabbit Monoclonal Antibody
Product Information
Downloads & Supports
Target
-
PF4
Host
Storage
-
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
Clone Number
-
R02-1E3
Isotype
-
IgG
Reactivity
Application
Application Details
-
WB: 1/500-1/1000 IHC: 1/50-1/100 IP: 1/20
Immunogen
-
A synthetic peptide of human PF4
Molecular Weight
-
Calculated MW: 11 kDa; Observed MW: 11 kDa
Formulation
-
50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
Form
-
Liquid
Gene ID
-
5196
Uniprot ID
-
P02776
Background
-
Released during platelet aggregation. Neutralizes the anticoagulant effect of heparin because it binds more strongly to heparin than to the chondroitin-4-sulfate chains of the carrier molecule. Chemotactic for neutrophils and monocytes. Inhibits endothelial cell proliferation, the short form is a more potent inhibitor than the longer form.
Research Area
-
Immunology
Synonyms
-
C-X-C motif chemokine 4; CXCL4; Iroplact; OncostatinA; PF4; Platelet factor 4; SCYB4; short form; Small inducible cytokine subfamily member 4