Anti-PDX1 Rabbit Monoclonal Antibody
Product Information
Downloads & Supports
Target
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PDX1
Host
Storage
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Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
Clone Number
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R03-6B9
Isotype
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IgG
Reactivity
Application
Application Details
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WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200
Immunogen
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A synthesized peptide derived from human PDX1
Molecular Weight
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Calculated MW: 31 kDa; Observed MW: 40 kDa
Formulation
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Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form
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Liquid
Gene ID
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3651
Uniprot ID
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P52945
Background
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The protein encoded by this gene is a transcriptional activator of several genes, including insulin, somatostatin, glucokinase, islet amyloid polypeptide, and glucose transporter type 2. The encoded nuclear protein is involved in the early development of the pancreas and plays a major role in glucose-dependent regulation of insulin gene expression.
Research Area
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Signal Transduction
Synonyms
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GSF; IPF1; IUF1; IDX-1; MODY4; PDX-1; STF-1