Anti-PAX6 Rabbit Monoclonal Antibody
Product Information
Downloads & Supports
Target
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PAX6
Host
Storage
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Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
Clone Number
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R03-8G4
Isotype
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IgG
Reactivity
Application
Application Details
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WB: 1/500-1/1000
Immunogen
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A synthetic peptide of human PAX6
Molecular Weight
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Calculated MW: 47 kDa; Observed MW: 47 kDa
Formulation
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50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
Form
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Liquid
Gene ID
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5080
Uniprot ID
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P26367
Background
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Transcription factor with important functions in the development of the eye, nose, central nervous system and pancreas. Required for the differentiation of pancreatic islet alpha cells (By similarity). Competes with PAX4 in binding to a common element in the glucagon, insulin and somatostatin promoters. Regulates specification of the ventral neuron subtypes by establishing the correct progenitor domains (By similarity).
Research Area
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Neuroscience
Synonyms
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PAX6; AN2; Paired box protein Pax-6; Aniridia type II protein; Oculorhombin