Anti-PARS2 Rabbit Polyclonal Antibody
Product Information
Downloads & Supports
Target
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PARS2
Host
Storage
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Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
Clone Number
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-
Isotype
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IgG
Reactivity
Application
Application Details
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WB: 1/500-1/1000 IHC: 1/50-1/100
Immunogen
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Fusion protein of human PARS2
Molecular Weight
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Calculated MW: 53 kDa; Observed MW: 53 kDa
Formulation
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pH 7.4 PBS, 0.05% NaN3, 40% Glycerol
Form
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Liquid
Gene ID
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25973
Uniprot ID
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Q7L3T8
Background
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This gene encodes a putative member of the class II family of aminoacyl-tRNA synthetases. These enzymes play a critical role in protein biosynthesis by charging tRNAs with their cognate amino acids. This protein is encoded by the nuclear genome but is likely to be imported to the mitochondrion where it is thought to catalyze the ligation of proline to tRNA molecules. Mutations have been found in this gene in some patients with Alpers syndrome.
Research Area
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Synonyms
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prolyl-tRNA synthetase 2; mitochondrial (putative); proRS; MT-PRORS