Anti-PAK2 (7H3) Mouse Monoclonal Antibody
Product Information
Downloads & Supports
Target
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PAK2
Host
Storage
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Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
Clone Number
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7H3-E2-F5
Isotype
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IgG1
Reactivity
Application
Application Details
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WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200
Immunogen
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Purified recombinant fragment of PAK2 expressed in E. Coli.
Molecular Weight
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Calculated MW: 58 kDa; Observed MW: 61 kDa
Formulation
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Ascitic fluid containing 0.03% sodium azide.
Form
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Liquid
Gene ID
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5062
Uniprot ID
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Q13177
Background
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The activated kinase acts on a variety of targets. Phosphorylates ribosomal protein S6, histone H4 and myelin basic protein. Full length PAK 2 stimulates cell survival and cell growth. The process is, at least in part, mediated by phosphorylation and inhibition of pro-apoptotic BAD.
Research Area
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Cell Biology
Synonyms
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PAK2; Serine/threonine-protein kinase PAK 2; Gamma-PAK; PAK65; S6/H4 kinase; p21-activated kinase 2; PAK-2; p58