Anti-PABPN1 Rabbit Monoclonal Antibody
Product Information
Downloads & Supports
Target
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PABPN1
Host
Storage
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Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
Clone Number
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R02-8B1
Isotype
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IgG
Reactivity
Application
Application Details
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WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200 IP: 1/20
Immunogen
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A synthetic peptide of human PABPN1
Molecular Weight
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Calculated MW: 33 kDa; Observed MW: 50 kDa
Formulation
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50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
Form
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Liquid
Gene ID
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8106
Uniprot ID
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Q86U42
Background
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Involved in the 3'-end formation of mRNA precursors (pre-mRNA) by the addition of a poly(A) tail of 200-250 nt to the upstream cleavage product. Stimulates poly(A) polymerase (PAPOLA) conferring processivity on the poly(A) tail elongation reaction and controls also the poly(A) tail length. Increases the affinity of poly(A) polymerase for RNA.
Research Area
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Epigenetics and Nuclear Signaling
Synonyms
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OPMD; PAB2; PABII; PABP2; PABP-2