Anti-p73 Rabbit Polyclonal Antibody
Product Information
Downloads & Supports
Target
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TP73
Host
Storage
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Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
Clone Number
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-
Isotype
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IgG
Reactivity
Application
Application Details
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WB: 1/500-1/1000 IHC: 1/50-1/100
Immunogen
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Fusion protein of human TP73
Molecular Weight
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Calculated MW: 70 kDa; Observed MW: 70 kDa
Formulation
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pH 7.4 PBS, 0.05% NaN3, 40% Glycerol
Form
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Liquid
Gene ID
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7161
Uniprot ID
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O15350
Background
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p73 IS a protein of the p53 family of proteins. Participates in the apoptotic response to DNA damage. Phosphorylated in a cell cycle-dependent manner and negatively regulated by CDKs. When overproduced, activates transcription from p53-responsive promoters and induces apoptosis. May be a tumor suppressor protein. Seven alternatively-spliced isoforms have been described.
Research Area
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Cell Biology
Synonyms
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TP73; P73; Tumor protein p73; p53-like transcription factor; p53-related protein