Anti-p27 Kip 1 Rabbit Monoclonal Antibody

Anti-p27 Kip 1 Rabbit Monoclonal Antibody
Anti-p27 Kip 1 Rabbit Monoclonal Antibody
Anti-p27 Kip 1 Rabbit Monoclonal Antibody
Anti-p27 Kip 1 Rabbit Monoclonal Antibody

Anti-p27 Kip 1 Rabbit Monoclonal Antibody

Rabbit IgG Monoclonal for CDKN1B detection, Test with WB, IHC-P, IP in Human, Mouse, Rat

Reactivity
  • Human
  • Mouse
  • Rat
Application
  • WB
  • IHC-P
  • IP
Host
  • Rabbit
Catalog Number
    ABXB61337
$370.00

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United States

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Target
    CDKN1B
Host
  • Rabbit
Storage
    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
  • Monoclonal
Clone Number
    R09-6C3
Isotype
    IgG
Reactivity
  • Human
  • Mouse
  • Rat
Application
  • WB
  • IHC-P
  • IP
Application Details
    WB: 1/500-1/1000 IHC: 1/50-1/100 IP: 1/20
Immunogen
    A synthetic peptide of human p27 KIP 1
Molecular Weight
    Calculated MW: 22 kDa; Observed MW: 27 kDa
Formulation
    50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
Form
    Liquid
Gene ID
    1027
Uniprot ID
    P46527
Background
    The encoded protein binds to and prevents the activation of cyclin E-CDK2 or cyclin D-CDK4 complexes, and thus controls the cell cycle progression at G1. The degradation of this protein, which is triggered by its CDK dependent phosphorylation and subsequent ubiquitination by SCF complexes, is required for the cellular transition from quiescence to the proliferative state.
Research Area
    Cell Biology
Synonyms
    CDKN1B; KIP1; Cyclin-dependent kinase inhibitor 1B; Cyclin-dependent kinase inhibitor p27; p27Kip1
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Product Image

Western blot analysis of p27 KIP 1 in 3T3, Hela lysates using p27 Kip 1 antibody.
Immunohistochemistry analysis of paraffin-embedded Human breast cancer using p27 KIP 1 antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.