Anti-Ornithine Carbamoyltransferase/OTC Rabbit Monoclonal Antibody
Product Information
Downloads & Supports
Target
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OTC
Host
Storage
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Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
Clone Number
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R02-1U-9
Isotype
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IgG
Reactivity
Application
Application Details
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IHC: 1/100-1/200
Immunogen
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A synthesized peptide derived from human Ornithine Carbamoyltransferase
Formulation
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Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.
Form
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Liquid
Gene ID
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5009
Uniprot ID
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P00480
Background
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This nuclear gene encodes a mitochondrial matrix enzyme. Missense, nonsense, and frameshift mutations in this enzyme lead to ornithine transcarbamylase deficiency, which causes hyperammonemia. Since the gene for this enzyme maps close to that for Duchenne muscular dystrophy, it may play a role in that disease also.
Research Area
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Tags & Cell Markers
Synonyms
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OTCase; Ornithine carbamoyltransferase; mitochondrial; OCTD