Anti-ORAI1 Rabbit Polyclonal Antibody
Product Information
Downloads & Supports
Target
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ORAI1
Host
Storage
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Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
Clone Number
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-
Isotype
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IgG
Reactivity
Application
Application Details
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WB: 1/500-1/1000
Immunogen
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This ORAI1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide from the Central region of human ORAI1.
Molecular Weight
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Calculated MW: 33 kDa; Observed MW: 54 kDa
Formulation
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Liquid in PBS containing 0.09% sodium azide, pH 7.3.
Form
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Liquid
Gene ID
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84876
Uniprot ID
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Q96D31
Background
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Ca(2+) release-activated Ca(2+) (CRAC) channel subunit which mediates Ca(2+) influx following depletion of intracellular Ca(2+) stores and channel activation by the Ca(2+) sensor, STIM1. CRAC channels are the main pathway for Ca(2+) influx in T-cells and promote the immune response to pathogens by activating the transcription factor NFAT.
Research Area
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Immunology
Synonyms
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CRACM1; Orai 1; ORAI calcium release activated calcium modulator 1; orai1; ORAT1; Protein orai 1; TMEM142A