Anti-OGG1 Rabbit Monoclonal Antibody
Product Information
Downloads & Supports
Target
-
OGG1
Host
Storage
-
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
Clone Number
-
R08-2F5
Isotype
-
IgG
Reactivity
Application
Application Details
-
WB: 1/500-1/1000
Immunogen
-
A synthesized peptide derived from human OGG1
Molecular Weight
-
Calculated MW: 39 kDa; Observed MW: 39 kDa
Formulation
-
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form
-
Liquid
Gene ID
-
4968
Uniprot ID
-
O15527
Background
-
DNA repair enzyme that incises DNA at 8-oxoG residues. Excises 7,8-dihydro-8-oxoguanine and 2,6-diamino-4-hydroxy-5-N-methylformamidopyrimidine (FAPY) from damaged DNA. Has a beta-lyase activity that nicks DNA 3' to the lesion.
Research Area
-
Epigenetics and Nuclear Signaling
Synonyms
-
8 hydroxyguanine DNA glycosylase; AP lyase; HMMH; HOGG1; MMH; MUTM; N glycosylase; Ogg1; OGH 1