Anti-Nup160 Rabbit Polyclonal Antibody
Product Information
Downloads & Supports
Target
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NUP160
Host
Storage
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Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Clonality
Clone Number
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Isotype
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IgG
Reactivity
Application
Application Details
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WB: 1/500-1/1000
Immunogen
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Synthetic peptide corresponding to Human Nup160.
Molecular Weight
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Calculated MW: 162kDa
Formulation
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1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.
Form
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Liquid
Gene ID
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23279
Uniprot ID
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Q12769
Background
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Nuclear pore complexes (NPCs) are the channels for the bi-directional movement of macromolecules between the nucleus and cytoplasm, and contain more than 100 different subunits. Many of them belong to a family called nucleoporins, which are characterized by the presence of O-linked N-acetylglucosamine moieties and a distinctive pentapeptide repeat (XFXFG).Nuclear pore complex protein Nup96 (Nup96) is formed by cleavage of a 186 kDa precursor protein. This proteolytic cleavage yields two nucleoporins,Nup98 and Nup96. Nup96 is part of the Nup160 subcomplex in the nuclear pore (which consists of Nup160, Nup133, Nup107 and Nup96). Nup96 plays a major role in the two-way transport across the nuclear pore and is important in RNA export.
Research Area
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Synonyms
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Nuclear pore complex protein Nup160; 160 kDa nucleoporin; Nucleoporin Nup160; NUP160; KIAA0197; NUP120