Anti-Nrf1 (9E6) Mouse Monoclonal Antibody
Product Information
Downloads & Supports
Target
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NRF1
Host
Storage
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Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
Clone Number
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9E6-H8-B6
Isotype
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IgG2a
Reactivity
Application
Application Details
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WB: 1/500-1/1000
Immunogen
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Purified recombinant human NRF1 protein fragments expressed in E.coli
Molecular Weight
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Calculated MW: 54 kDa; Observed MW: 72 kDa
Formulation
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Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.
Form
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Liquid
Gene ID
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4899
Uniprot ID
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Q16656
Background
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Transcription factor that activates the expression of the EIF2S1 (EIF2-alpha) gene. Links the transcriptional modulation of key metabolic genes to cellular growth and development. Implicated in the control of nuclear genes required for respiration, heme biosynthesis, and mitochondrial DNA transcription and replication.
Research Area
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Epigenetics and Nuclear Signaling
Synonyms
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alpha pal; alpha palindromic binding protein; Alpha palindromic-binding protein; Alpha-pal; locus control region factor 1; NFE2 related factor 1; NRF-1; Nrf1; NRF1_HUMAN; Nuclear respiratory factor 1; transcription factor 11.