Anti-NQO1 Rabbit Monoclonal Antibody
Product Information
Downloads & Supports
Target
-
NQO1
Host
Storage
-
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
Clone Number
-
R02-4D6
Isotype
-
IgG
Reactivity
Application
Application Details
-
WB: 1/500-1/1000 IP: 1/20
Immunogen
-
A synthetic peptide of human NQO1
Molecular Weight
-
Calculated MW: 31 kDa; Observed MW: 31 kDa
Formulation
-
50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
Form
-
Liquid
Gene ID
-
1728
Uniprot ID
-
P15559
Background
-
NAD(P)H:quinone oxidoreductase 1 (NQO1) is a flavoprotein that catalyzes the two-electron reduction of quinones and their derivatives. The enzyme apparently serves as a quinone reductase in connection with conjugation reactions of hydroquinons involved in detoxification pathways as well as in biosynthetic processes such as the vitamin K-dependent gamma-carboxylation of glutamate residues in prothrombin synthesis.
Research Area
-
Signal Transduction
Synonyms
-
NQO1; DIA4; NMOR1; NAD(P)H dehydrogenase [quinone] 1; Azoreductase; DT-diaphorase; DTD; Menadione reductase; NAD(P)H:quinone oxidoreductase 1; Phylloquinone reductase; Quinone reductase 1; QR1