Anti-NLK Rabbit Monoclonal Antibody
Product Information
Downloads & Supports
Target
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NLK
Host
Storage
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Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
Clone Number
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R03-2K8
Isotype
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IgG
Reactivity
Application
Application Details
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WB: 1/500-1/1000 FC: 1/50-1/100
Immunogen
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A synthesized peptide derived from human NLK
Molecular Weight
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Calculated MW: 58 kDa; Observed MW: 58 kDa
Formulation
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Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form
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Liquid
Gene ID
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51701
Uniprot ID
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Q9UBE8
Background
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Role in cell fate determination, required for differentiation of bone marrow stromal cells. Acts downstream of MAP3K7 and HIPK2 to negatively regulate the canonical Wnt/beta-catenin signaling pathway and the phosphorylation and destruction of the MYB transcription factor.
Research Area
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-
Synonyms
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LAK1; Nemo like kinase; Nlk