Anti-Niemann Pick C1 Rabbit Monoclonal Antibody
Product Information
Downloads & Supports
Target
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NPC1
Host
Storage
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Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
Clone Number
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R02-4L7
Isotype
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IgG
Reactivity
Application
Application Details
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WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200 FC: 1/50-1/100
Immunogen
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A synthesized peptide derived from human Niemann Pick C1
Molecular Weight
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Calculated MW: 142 kDa; Observed MW: 180 kDa
Formulation
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Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form
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Liquid
Gene ID
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4864
Uniprot ID
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O15118
Background
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Involved in the intracellular trafficking of cholesterol. May play a role in vesicular trafficking in glia, a process that may be crucial for maintaining the structural and functional integrity of nerve terminals.
Research Area
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Neuroscience
Synonyms
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Niemann Pick C1 protein precursor; NPC; NPC1