Anti-Niemann Pick C1 Like 1 Rabbit Monoclonal Antibody
Product Information
Downloads & Supports
Target
-
NPC1L1
Host
Storage
-
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
Clone Number
-
R09-2H3
Isotype
-
IgG
Reactivity
Application
Application Details
-
WB: 1/500-1/1000
Immunogen
-
A synthesized peptide derived from human NPC1L1
Molecular Weight
-
Calculated MW: 149 kDa
Formulation
-
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form
-
Liquid
Gene ID
-
29881
Uniprot ID
-
Q9UHC9
Background
-
Play a major role in cholesterol homeostasis. Is critical for the uptake of cholesterol across the plasma membrane of the intestinal enterocyte. Is the direct molecular target of ezetimibe, a drug that inhibits cholesterol absorbtion.
Research Area
-
Neuroscience
Synonyms
-
NPC1 LIKE 1; NPC1L1