Anti-NFE2L2(L30F Mutant) Mouse Monoclonal Antibody

Anti-NFE2L2(L30F Mutant) Mouse Monoclonal Antibody
Anti-NFE2L2(L30F Mutant) Mouse Monoclonal Antibody
Anti-NFE2L2(L30F Mutant) Mouse Monoclonal Antibody
Anti-NFE2L2(L30F Mutant) Mouse Monoclonal Antibody

Anti-NFE2L2(L30F Mutant) Mouse Monoclonal Antibody

Mouse IgG Monoclonal for NFE2L2, NRF2 detection, Test with WB, IHC-P, ELISA in Vertebrates

Reactivity
  • Vertebrates
Application
  • WB
  • IHC-P
  • ELISA
Host
  • Mouse
Catalog Number
    ABXB07360
$680.00

Shipping To:
United States

Product Information

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Target
    NFE2L2, NRF2
Host
  • Mouse
Storage
    Store at -20°C. Avoid repeated freezing and thawing
Clonality
  • Monoclonal
Clone Number
    3E8-X1-N6
Isotype
    IgG
Reactivity
  • Vertebrates
Application
  • WB
  • IHC-P
  • ELISA
Application Details
    ELISA: 1/1000-1/2000 WB: 1/500-1/1000 IHC-P: 1/50-1/100
Immunogen
    A synthetic peptide from the internal region of NFE2L2 which includes the mutation of L30F, human origin.
Formulation
    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol
Form
    Liquid
Uniprot ID
    ­
Background
    NFE2L2 protein is encoded by NFE2L2 gene. It is a basic leucine zipper protein that regulates the expression of antioxidant proteins that protect against oxidative damage triggered by injury and inflammation. Several drugs that stimulate the NFE2L2 pathway are being studied for treatment of diseases that are caused by oxidative stress.
Research Area
    Epigenetics and Nuclear Signaling
Synonyms
    NFE2L2, NRF2
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Product Image

Western blot analysis of recombinant NFE2L2(L30F) and wild type proteins. Purified His-tagged NFE2L2(L30F) protein (lane2) and corresponding wild type protein (lane1) were blotted with Anti-NFE2L2(L30F) monoclonal.
Immunofluorescence of cells expressing NFE2L2 proteins with Anti-NFE2L2(L30F). HEK293T cells were transfected with pCDNA3-GFP-NFE2L2 (WT) plasmid (left column) or pCDNA3-GFP-NFE2L2(L30F) plasmid (right column), then fixed and stained with Anti-NFE2L2(L30F) monoclonal.