Anti-NF-KB p65 (5A10) Mouse Monoclonal Antibody
Product Information
Downloads & Supports
Target
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RELA
Host
Storage
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Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
Clone Number
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5A10-1F10-1D8
Isotype
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IgG1
Reactivity
Application
Application Details
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WB: 1/500-1/1000 IHC: 1/50-1/100 IP: 1/20
Immunogen
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Synthetic Peptide of NFkB p65
Molecular Weight
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Calculated MW: 60 kDa; Observed MW: 65 kDa
Formulation
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Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.
Form
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Liquid
Gene ID
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5970
Uniprot ID
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Q04206
Background
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NFKB1 (MIM 164011) or NFKB2 (MIM 164012) is bound to REL (MIM 164910), RELA, or RELB (MIM 604758) to form the NFKB complex. The p50 (NFKB1)/p65 (RELA) heterodimer is the most abundant form of NFKB. The NFKB complex is inhibited by I-kappa-B proteins (NFKBIA, MIM 164008 or NFKBIB, MIM 604495), which inactivate NFKB by trapping it in the cytoplasm.
Research Area
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Cell Biology
Synonyms
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NFKB3; RELA; TF65; Transcription factor p65; p65; NFkB