Anti-NF-KB p105 (5E3) Mouse Monoclonal Antibody
Product Information
Downloads & Supports
Target
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NFKB1
Host
Storage
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Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
Clone Number
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5E3-E4-C11
Isotype
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IgG1
Reactivity
Application
Application Details
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WB: 1/500-1/1000
Immunogen
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Recombinant human NF-κB1 p105/p50 protein.
Molecular Weight
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Calculated MW: 105 kDa; Observed MW: 50,120 kDa
Formulation
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Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.
Form
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Liquid
Gene ID
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4790
Uniprot ID
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P19838
Background
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NFkB-p105 a transcription factor of the nuclear factor-kappaB ( NFkB) group. Undergoes cotranslational processing by the 26S proteasome to produce a 50 kD protein. The 105 kD protein is a Rel protein-specific transcription inhibitor and the 50 kD protein is a DNA binding subunit of NFkB. NFkB is a transcription regulator that is activated by various intra- and extra-cellular stimuli such as cytokines, oxidant-free radicals, ultraviolet irradiation, and bacterial or viral products.
Research Area
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Cell Biology
Synonyms
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NFKB1; Nuclear factor NF-kappa-B p105 subunit; DNA-binding factor KBF1; EBP-1; Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1