Anti-Neurokinin 1 Receptor Rabbit Monoclonal Antibody
Product Information
Downloads & Supports
Target
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TACR1
Host
Storage
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Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
Clone Number
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R05-3D1
Isotype
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IgG
Reactivity
Application
Application Details
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WB: 1/500-1/1000 IP: 1/20
Immunogen
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A synthetic peptide of human Neurokinin 1 Receptor
Molecular Weight
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Calculated MW: 46 kDa; Observed MW: 46 kDa
Formulation
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50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
Form
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Liquid
Gene ID
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6869
Uniprot ID
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P25103
Background
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This is a receptor for the tachykinin neuropeptide substance P. It is probably associated with G proteins that activate a phosphatidylinositol-calcium second messenger system. The rank order of affinity of this receptor to tachykinins is: substance P > substance K > neuromedin-K.
Research Area
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Neuroscience
Synonyms
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TACR1; NK1R; TAC1R; Substance-P receptor; SPR; NK-1 receptor; NK-1R; Tachykinin receptor 1