Anti-n Myc Rabbit Polyclonal Antibody
Product Information
Downloads & Supports
Target
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MYCN
Host
Storage
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Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
Clone Number
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-
Isotype
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IgG
Reactivity
Application
Application Details
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WB: 1/500-1/1000 IHC: 1/50-1/100
Immunogen
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Synthetic peptide of human MYCN
Molecular Weight
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Calculated MW: 50 kDa; Observed MW: 50 kDa
Formulation
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pH 7.4 PBS, 0.05% NaN3, 40% Glycerol
Form
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Liquid
Gene ID
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4613
Uniprot ID
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P04198
Background
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This gene is a member of the MYC family and encodes a protein with a basic helix-loop-helix (bHLH) domain. This protein is located in the nucleus and must dimerize with another bHLH protein in order to bind DNA. Amplification of this gene is associated with a variety of tumors, most notably neuroblastomas. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Research Area
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Epigenetics and Nuclear Signaling
Synonyms
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NMYC; ODED; MODED; N-myc; bHLHe37