Anti-Myosin Light Chain 2 Rabbit Monoclonal Antibody
Product Information
Downloads & Supports
Target
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MYL2
Host
Storage
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Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
Clone Number
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R03-1V-4
Isotype
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IgG
Reactivity
Application
Application Details
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IHC: 1/100-1/200
Immunogen
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A synthesized peptide derived from human Myosin Light Chain 2
Formulation
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Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.
Form
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Liquid
Gene ID
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4633
Uniprot ID
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P10916
Background
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Myosin is composed of six polypeptide chains: two identical heavy chains and two pairs of light chains. Myosin light chain 2 (MLC2), also known as myosin regulatory light chain (MRLC), RLC, or LC20, has many isoforms depending on its distribution. In smooth muscle, MLC2 is phosphorylated at Thr18 and Ser19 by myosin light chain kinase (MLCK) in a Ca2+/calmodulin-dependent manner.
Research Area
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Signal Transduction
Synonyms
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MYL2;Myosin regulatory light chain 2; ventricular/cardiac muscle isoform; MLC-2; MLC-2v