Anti-MyD88 Rabbit Monoclonal Antibody
Product Information
Downloads & Supports
Target
-
MYD88
Host
Storage
-
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
Clone Number
-
R04-5E7
Isotype
-
IgG
Reactivity
Application
Application Details
-
WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200 FC: 1/50-1/100
Immunogen
-
A synthesized peptide derived from human MyD88
Molecular Weight
-
Calculated MW: 33 kDa; Observed MW: 33 kDa
Formulation
-
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form
-
Liquid
Gene ID
-
4615
Uniprot ID
-
Q99836
Background
-
Members of the Toll-like receptor (TLR) family, named for the closely related Toll receptor in Drosophila, play a pivotal role in innate immune responses. TLRs recognize conserved motifs found in various pathogens and mediate defense responses. Triggering of the TLR pathway leads to the activation of NF-κB and subsequent regulation of immune and inflammatory genes.
Research Area
-
Signal Transduction
Synonyms
-
MYD88; Myeloid differentiation primary response protein MyD88