Anti-Mucin 5AC Mouse Monoclonal Antibody
Product Information
Downloads & Supports
Target
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MUC5AC
Host
Storage
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Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
Clone Number
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6E2-5E5-2A6
Isotype
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IgG
Reactivity
Application
Application Details
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IHC: 1/100-1/500
Immunogen
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Synthesized peptide derived from human MUC5AC
Molecular Weight
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-
Formulation
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Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.
Form
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Liquid
Gene ID
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4586
Uniprot ID
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P98088
Background
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Gastric Mucin 5AC antigen is found in columnar mucus cells of surface gastric epithelium and in goblet cells of the fetal and precancerous colon but not in normal colon. Resurgence of gastric mucin during colonic carcinogenesis is suggestive of either re-expression of the peptide core of gastric mucin in the adult colon or due to changes in the glycosylation pattern of mucin, which expose the hidden Mucin 5AC antigen.
Research Area
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Signal Transduction
Synonyms
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Apomucin; Gastric mucin; LeB; MUC5AC; Mucin 5AC oligomeric mucus/gel forming; TBM