Anti-MUC-4 Rabbit Monoclonal Antibody
Product Information
Downloads & Supports
Target
-
MUC4
Host
Storage
-
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Clonality
Clone Number
-
R09-5G-2
Isotype
-
IgG
Reactivity
Application
Application Details
-
IHC-P:1/50-1/100
Immunogen
-
Peptide
Molecular Weight
-
–
Formulation
-
Liquid in PBS, Glycerol and BSA
Form
-
Liquid
Gene ID
-
4585
Uniprot ID
-
Q99102
Background
-
May play a role in tumor progression. Ability to promote tumor growth may be mainly due to repression of apoptosis as opposed to proliferation. Has anti-adhesive properties. Seems to alter cellular behavior through both anti-adhesive effects on cell-cell and cell-extracellular matrix interactions and in its ability to act as an intramembrane ligand for ERBB2. Plays an important role in cell proliferation and differentiation of epithelial cells by inducing specific phosphorylation of ERBB2.
Research Area
-
Cell Biology
Synonyms
-
ASGP, Mucin-4 alpha chain, ASGP-1, Testis mucin, Pancreatic adenocarcinoma mucin